Sulfamethoxazole/Trimethoprim induced liver failure: a case report

Sulfamethoxazole/Trimethoprim (SMX/TMP) is a commonly used antibiotic, its' known adverse reaction of hepatotoxicity leading to acute liver failure is considered rare. We present a case of a 22 year old female who developed jaundice and acute liver failure one week after taking SMX/TMP for a UTI.

After an extensive work up, a clinical diagnosis of SMX/TMP induced liver failure was reached. Over the course of several weeks she made a good clinical and biochemical recovery with supportive care.

In this case report we describe her clinical presentation and course, and present a brief review of the literature.

Author: SalaheldinAbusin and Swapna Johnson
Credits/Source: Cases Journal 2008, 1:44

Published on: 2008-07-18

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