Paget's disease of the skull causing hyperprolactinemia and erectile dysfunction: a case report

IntroductionHyperprolacinemia is an uncommon cause of erectile dysfunction in men. Paget's disease of the skull is a relatively common disease.

This case proposes a rare example of a causative link between the two and how treatment of the Paget's disease with bisphosphonates helped the patient regain erectile function.Case presentationA 67-year-old man with Paget's disease of the skull presented with prostatitis, erectile dysfunction, and hyperprolactinemia. Radio-isotope scanning showed increased vascularity around the sphenoid bone.

Treatment with intravenous bisphosphonates improved the active Paget's disease as indicated by declining alkaline phosphatase levels and the patient's erectile function while serum prolactin levels became normal and serum testosterone levels remained unchanged.

Conclusion: It is possible that hyperprolactinemia is unrecognised in other patients with Paget's disease of the skull. Normalizing elevated prolactin levels by using bisphosphonates in treating Paget's disease appears to be more appropriate than traditional treatment for hyperprolactinemia.

Author: Rachel Hepherd and Paul E Jennings
Credits/Source: Journal of Medical Case Reports 2008, 2:234

Published on: 2008-07-18

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Comments Page 1 of 1

Impotence

Posted 174 days ago

Issue should be considered at high priority and remedy should be found at the earliest.
http://www.onlineclinic.co.uk/impoten ce.html

Erectile dysfunction

Posted 174 days ago

People need to take precautions and a remedy should be found at the earliest so that the issue of Impotence doesn't become a major issue.

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