A simple hepatic cyst with elevated serum and cyst fluid CA19-9 levels: a case report
IntroductionSimple hepatic cysts rarely cause symptoms, however, occasionally they become symptomatic due to mass effect, rupture, hemorrhage, and infection. We report a patient with a large hepatic cyst with elevated serum and cyst fluid CA19-9 levels.
We studied serum and cyst fluid CA19-9 levels in this patient, before and after the intracystic instillation of minocycline hydrochloride.Case presentationA 76-year-old Japanese woman was diagnosed as having an infected hepatic cyst, by physical examination and enhanced abdominal computed tomography. Serum (170U/ml; reference: <37U/ml) and hepatic cyst fluid (371U/ml) CA19-9 levels were elevated.
After the intracystic instillation of minocycline hydrochloride, necrotic cells in the cyst weredrained, and it totally collapsed after 1 week. Cyst fluid CA19-9 levels increased remarkably after the intracystic instillation of minocycline hydrochloride, while serum CA19-9 levels decreased significantly.
Conclusion: Our study is the first report to reveal the influence of intracystic instillation of minocycline hydrochloride on serum and cyst fluid CA19-9 levels in a patient with a simple hepatic cyst.
Author: Hidekatsu Yanai and Norio Tada
Credits/Source: Journal of Medical Case Reports 2008, 2:329
Published on: 2008-10-14
Copyright by the authors listed above - made available via BioMedCentral (Open Access). Please
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