Colonization and/or infection with methicillin-resistant Staphylococcus aureus after living donor liver transplantation: a case control study
The incidence and risk factors of methicillin-resistant Staphylococcus aureus (MRSA) acquisition after living donor liver transplantation (LDLT) are unclear. The aim of the present study was to assess the incidence and to analyze therisk factors for the acquisition of MRSA after LDLT in adults by multivariate analysis.
Methods: We retrospectively reviewed the data from 158 adult patients that underwent LDLT at the Tokyo University Hospital. The microbiologic and medical records of the patients from admission to 3 months after LDLT were reviewed.
Uni- and multivariate analyses were performed to identify the risk factors for postoperative acquisition of MRSA.
Results: Postoperative MRSA acquisition was detected in 35 of 158 patients by median postoperative day 18.
Age (>= 60 y) and perioperative dialysis and/or apheresis predicted postoperative MRSA acquisition by multivariate analysis. In contrast, postoperative use of fluoroquinolone was negatively associated with acquisition of MRSA.
Conclusion: MRSA arises early after LDLT in adults with a high incidence (35 of 158 patients).
Surveillance culture should be checked periodically after LDLT to identify and prevent the transmission of MRSA.
Author: Masao Hashimoto, Yasuhiko Sugawara, Sumihito Tamura, Junichi Kaneko, Yuichi Matsui, Junichi Togashi, Kyoji Moriya, Kazuhiko Koike and Masatoshi Makuuchi
Credits/Source: BMC Infectious Diseases 2008, 8:155
Published on: 2008-11-12
Copyright by the authors listed above - made available via BioMedCentral (Open Access). Please
make sure to read our disclaimer prior to contacting 7thSpace Interactive. To contact our editors, visit our online helpdesk. If you wish submit your own press release, click here.
Social Bookmarking
RETWEET This! | Digg this! | Post to del.icio.us | Post to Furl | Add to Netscape | Add to Yahoo! | Rojo
|
|
