Delayed malignant melanoma recurrence simulating primary ovarian cancer


Metastatic involvement of the ovary from malignant melanoma is uncommon and presents a diagnostic challenge. Most cases are associated with disseminated disease and carry a dismal prognosis.

Delayed ovarian recurrences from melanoma may mimic primary ovarian cancer and lead to aggressive cytoreductive procedures. Case presentationA case of malignant melanoma in a premenopausal patient is presented with late abdominal and ovarian metastatic spread, where ascitic fluid cytology led to an accurate preoperative diagnosis and the avoidance of unnecessary surgical procedures.

Conclusions: Secondary ovarian involvement is associated with a poor prognosis and efforts should be made for adequate palliation.

Pathologic diagnosis with non-invasive procedures is crucial in order to avoid unnecessary surgery. Surgical interventions may be undertaken only in selected cases of limited metastatic disease, where complete resection is expected

Author: Anastasios Boutis, Rosalia Valeri, Ippokratis Korantzis, Dimitrios Valoukas, Ioannis Andronikidis and Charalambos Andreadis
Credits/Source: World Journal of Surgical Oncology 2008, 6:124



Published on: 2008-11-20

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