Management of renal nutcracker syndrome by retroperitoneal laparoscopic nephrectomy with ex vivo autograft repair and autotransplantation: a case report and review of the literature


IntroductionNutcracker syndrome (NCS) is caused by a compression of the left renal vein between the aorta and the superior mesenteric artery (SMA). It results in left renal venous hypertension, and the subsequent development of venous varicosities of the renal pelvis, ureter, and gonadal vein.Case presentationA 21-year-old Chinese woman was admitted with a seven-month history of unilateral severe hematuria.

On admission, she was identified as having nutcracker syndrome. The patient was treated with retroperitoneal laparoscopic donor nephrectomy and renal autotransplantation.

The patient underwent retroperitoneal laparoscopic donor nephrectomy using a retroperitoneal three-port technique with ex vitro autograft repair and subsequent renal autotransplantation into the iliac fossa. In order to shorten the hot ischemia time and improve the patient's cosmetic outcome, a minor oblique incision in the left, lower quadrant was prepared in advance of the laparoscopic donor nephrectomy for use as a site for the autograft to be procured through the retroperitoneal space and as a transplant site for the autograft.

Two days after the operation, the patient's symptoms subsided. Serum creatinine before and after the operation were 53mmol/L and 55mmol/L, respectively.

The patient had normal renal function during a follow-up three months after the operation.

Conclusions: The treatment of nutcracker syndrome by retroperitoneal laparoscopic nephrectomy with ex vitro repair and autotransplantation is a simpler and less invasive procedure than open surgery. Moreover, a minor incision on the left hypogastrium can shorten the autograft's hot ischemic time and improve patients'cosmetic outcomes, especially in young women.

Author: Danfeng XuYushan LiuGao YiLei ZhangJunkai WangJiangping CheYouhua Zhu
Credits/Source: Journal of Medical Case Reports 2009, 3:82



Published on: 2009-10-27

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