Prediction of post-operative necrosis after mastectomy: A pilot study utilizing optical diffusion imaging spectroscopy
IntroductionFlap necrosis and epidermolysis occurs in 18-30% of all mastectomies. Complications may be prevented by intra-operative detection of ischemia.
Currently, no technique enables quantitative valuation of mastectomy skin perfusion. Optical Diffusion Imaging Spectroscopy (ViOptix T.Ox Tissue Oximeter) measures the ratio of oxyhemoglobin to deoxyhemoglobin over a 1x1cm area to obtain a non-invasive measurement of perfusion (StO2).
Methods: This study evaluates the ability of ViOptix T.Ox Tissue Oximeter to predict mastectomy flap necrosis.
StO2 measurements were taken at five points before and at completion of dissection in 10 patients. Data collected included: demographics, tumor size, flap length/thickness, co-morbidities, procedure length, and wound complications.
Results: One patient experienced mastectomy skin flap necrosis.
Five patients underwent immediate reconstruction, including the patient with necrosis. Statistically significant factors contributingto necrosis included reduction in medial flap StO2 (p=0.0189), reduction in inferior flap StO2 (p=0.003), and flap length (p=0.009).
Conclusion: StO2 reductions may be utilized to identify impaired perfusion in mastectomy skin flaps.
Author: Roshni RaoMichel Saint-CyrAye MaMonet BowlingDaniel HatefValerie AndrewsXian-Jin XieTheresa ZogakisRod Rohrich
Credits/Source: World Journal of Surgical Oncology 2009, 7:91
Published on: 2009-11-25
Copyright by the authors listed above - made available via BioMedCentral (Open Access). Please
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