Duloxetine for treatment of male sphincteric incontinence following partial conus medullaris infarction after coronary bypass surgery

IntroductionVascular spinal cord injury following coronary bypass grafting surgery is very rare and this is probably one of few reports of a presumptive partial conus medullaris lesion leading to sudden onset bladder and bowel incontinence which was managed using duloxetine, a selective serotonin and norepinephrine reuptake inhibitor. Duloxetine has been used in selected patients with post-prostatectomy sphincteric incontinence but not, to our knowledge, for spinal vascular lesions.Case presentationA 63-year-old Indian man developed bladder and bowel incontinence immediately following coronary bypass grafting surgery.

Findings were suggestive of microcirculatory partial conus medullaris infarction. Based on his urodynamics findings he was managed with duloxetine, tolterodine and clean intermittent catheterization.

The clinical presentation, serial urodynamic findings and implications are discussed.

Conclusion: Spinal injury following coronary bypass grafting is rare and devastating. It is important to be able to recognize the problem even when paraplegia is not noted, counsel the patient and manage the patient with the help of urodynamics.

In patients withsphincteric incontinence, duloxetine may have a role in management.

Author: Sanjay SinhaSreenivasa SirigiriSrinivas KanakamedalaManoj SinghRakesh Sharma
Credits/Source: Cases Journal 2009, 2:9094

Published on: 2009-11-26

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