Influenza A (H1N1) in Rome, Italy in family: three case reports
IntroductionA new Influenza A virus H1N1 appeared in March-April 2009, and thousands of cases are reported worldwide. In the initial months, several imported cases are reported in many European countries, while some countries reported local chains of transmission.
We describe the first cluster of in-country transmission of the new Influenza A H1N1 which occurred in Italy, involving 3 patients.Case presentationPatient 1, a 11-year-old male child developed fever, cough, and general malaise 4 days after after returning from a travel to Mexico. Some days later, also the 69-year-old grandfather (patient 2), who did not travel to Mexico, and the 33-month-old brother (patient 3) of patient 1 developed mild influenza symptoms.
PCR tests resulted positive for Influenza A, and sequence analysis confirmed infection with the new Influenza A (H1N1) strain for all described patients. Some problems have been experienced in the administration of chemoprophylaxis and therapy in the patient 3.
The chemoprophylaxis policies in other family members are described, too.
Conclusion: Some interesting remarks emerge from the analysis of this cluster. The transmission of Influenza A H1N1 virus seems to be dependent on strict contacts, as household contacts.
Patient 2 and patient 3 did not assume or assumed not properly the chemoprophylaxis, respectively. The problems in the administration of chemoprophylaxis and therapy to patient 3 suggest that in infants specific individual-based strategies for assuring the correct administration are advisable.
Author: Francesco LisenaLicia BordiFabrizio CarlettiConcetta CastillettiFederica FerraroEleonora LalleSimone LaniniLuca Enrico RuscittiFrancesco Maria Fusco
Credits/Source: Cases Journal 2009, 2:9123
Published on: 2009-12-01
Copyright by the authors listed above - made available via BioMedCentral (Open Access). Please
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