Unusual presentation of eosinophilic fasciitis: Report of two cases and literature review


IntroductionEosinophilic fasciitis (EF) is an uncommon disorder with unknown etiology and its pathogenesis is poorly understood. We present two cases of EF with unusual presentation, and describe their clinical characteristics and laboratory findings.Case PresentationThe first case was a 29-year-old man admitted with pain, edema, and induration of the right-upper and left-lower limbs.

There was unilateral edema and stiffness with prominent pretibial edema upon physical examination, and a high eosinophil count on peripheral smear. The second case was a 63-year-old man who had pain, edema, erythema, and itching on the upper and lower extremities, which developed after strenuous physical activity.

He had cervical lymphadenopathy and polyarthritis upon physical examination, and rheumatoid factor and antinuclear antibody upon laboratory examination.

Conclusions: Eosinophilic fasciitis can present with various symptoms. When patients exhibit eosinophilia, arthralgia, and myalgia, EF should be considered as a possible diagnosis.

Author: Ramazan DanisSami AkbulutAbdullah AltintasSehmus OzmenCihan Akgul Ozmen
Credits/Source: Journal of Medical Case Reports 2010, 4:46



Published on: 2010-02-08

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