Limited educational attainment and radiographic and symptomatic knee osteoarthritis: a cross-sectional analysis using data from the Johnston County (North Carolina) Osteoarthritis Project
IntroductionApplying a cross-sectional analysis to a sample of 2627 African American and Caucasian adults aged [greater than or equal to]45 years from the Johnston County Osteoarthritis Project, we studied the association between educational attainment and prevalence of radiographic knee osteoarthritis and symptomatic knee osteoarthritis.
Methods: Age- and race-adjusted associations between education and osteoarthritis outcomes were assessed by gender-stratified logistic regression models, with additional models adjusting for body mass index, knee injury, smoking, alcohol use, and occupational factors.
Results: In an analysis of all participants, low educational attainment (<12 years) was associated with higher prevalence of 4 knee osteoarthritis outcomes (unilateral and bilateral radiographic and symptomatic osteoarthritis). Women with low educational attainment had 50% higher odds of having radiographic knee osteoarthritis and 65% higher odds of symptomatic knee osteoarthritis compared with those with higher educational attainment ([greater than or equal to]12 years), using fully adjusted models.
In the subset of postmenopausal women, these associations tended to be weaker but little affected by adjustment for hormone replacement therapy. Men with low educational attainment had 85% higher odds of having symptomatic knee osteoarthritis using fully adjusted models, but the association with radiographic knee osteoarthritis was explained by age.
Conclusions: After adjustment for known risk factors, educational attainment, as an indicator of socioeconomic status, is associated with symptomatic knee osteoarthritis in both men and women and with radiographic knee osteoarthritis in women.
Author: Leigh CallahanJack ShrefflerBernadette SiatonCharles HelmickBritta SchosterTodd SchwartzJiu-Chiuan ChenJordan RennerJoanne Jordan
Credits/Source: Arthritis Research &Therapy 2010, 12:R46
Published on: 2010-03-18
Copyright by the authors listed above - made available via BioMedCentral (Open Access). Please
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