Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial
Multifamily group psychoeducation (MFG) has been shown to reduce relapse rates among individuals with first-episode psychosis. However, given the cognitive demands associated with participating in this intervention (e.g ., learning and applying a structured problem-solving activity), the cognitive deficits that accompany psychotic disorders may limit the ability of certain individuals to benefit from this intervention.
Thus, the goal of this study is to examine whether individuals with first-episode psychosis who participate simultaneously in MFG and cognitive remediation--an intervention shown to improve cognitive functioning among individuals with psychotic disorders--will be less likely to experience a relapse than individuals who participate in MFG alone.
Methods:
Forty individuals with first-episode psychosis and their caregiving relative will be recruited to participate in this study. Individuals with first-episode psychosiswill be randomized to one of two conditions: (i) MFG with concurrent participation in cognitive remediation or (ii) MFG alone.
The primary outcome for this study is relapse of psychotic symptoms. We will also examine secondary outcomes among both individuals with first-episode psychosis (i.e ., social and vocational functioning, health-related quality of life, service utilization, independent living status, and cognitive functioning) and their caregiving relatives (i.e ., caregiver burden, anxiety, and depression)DiscussionCognitive remediation offers the possibility of ameliorating a specific deficit (i.e ., deficits in cognitive functioning) that often accompanies psychotic symptoms and may restrict the magnitude of the clinical benefits derived from MFG.Trial Registration: ClinicalTrials.gov Identifier NCT01196286
Author: Nicholas BreitbordeFrancisco MorenoNatalie Mai-DixonRachele PetersonLinda DurstBeth BernsteinSeenaiah ByreddyWilliam McFarlane
Credits/Source: BMC Psychiatry 2011, 11:9
Published on: 2011-01-12
Copyright by the authors listed above - made available via BioMedCentral (Open Access). Please
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