Efficacy of a combination of 10% imidacloprid and 1% moxidectin against Caparinia tripilis in African pygmy hedgehog (Atelerix albiventris)
The efficacy and safety of a combination formulation of 10% imidacloprid + 1.0% moxidectin spot-on (Advocate(R) for Cats, Bayer Animal Health GmbH, Leverkusen, Germany) were tested in 40 African pygmy hedgehogs (Atelerix albiventris) naturally infested with Caparinia tripilis.
The optimal dosage level of the combination for hedgehogs were determined by assigning 20 hedgehogs into three treatment (0.1, 0.4 and 1.6 ml/Kg b.w.) and one untreated control groups of 5 hedgehogs each. Twenty naturally infested hedgehogs were then randomly assigned to either treatment or control group with 10 animals each, and the number of live mites was counted from 13 body regions on day 0, 3, 9, 16 and 30 after single treatment at the dosage level of 0.1 ml/Kg.
Before the chemotherapy, the highest density of mite was observed in external ear canals followed by the dorsal and the lowest in the ventral regions of the body surface.
The dosage level of 0.1 ml/Kg which corresponded to the recommended dosage level of cat containing 10 mg imidacloprid and 1 mg moxidectin was also the optimal dosage level for hedgehogs, too. No hedgehogs in the treatment group showed live mites from day 3 post treatment.
Side effects such as ataxia, depression, nausea, weight fluctuation were not observed during the whole period of study.
This report suggests that a combination formulation of 0.1 ml/Kg of 10% imidacloprid + 1% moxidectin spot-on for cats is also useful for the control of Caparinia tripilis in hedgehogs.
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