Psychometric evaluation of the Taiwan Chinese version of the EORTC QLQ-PR25 for HRQOL assessment in prostate cancer patients


ObjectiveTo evaluate the psychometric properties of the Taiwan Chinese Version of the EORTC QLQ-PR25 health-related quality of life (HRQOL) questionnaire for patients with prostate cancer.

Methods: 135 prostate cancer patients were recruited in the urology outpatient clinic of a university teaching hospital. Each patient completed the EORTC QLQ-PR25 at every clinic visit between 2004 and 2008, totaling 633 assessments.

Confirmatory factor analysis and Rasch analysis were used to evaluate the domain- and item-level psychometric properties.

Results: The results supported the unidimensionality of each of the four EORTC QLQ-PR25 domains (urinary, bowel, and hormonal-treatment-related symptoms, and sexual functioning). Item calibrations for each domain were found invariant across the three assessment time periods.

The item-person maps showed 71.3 % of item coverage for the urinary symptoms domain and 13--42.7 % for the other three domains.

Conclusions: The Taiwan Chinese Version of the EORTC QLQ-PR25 questionnaire is reliable and can be used to measure HRQOL over time. Adding new items to each domain may improve its clinical content coverage and measurement precision.

Author: Yu-Jun ChangWen-Miin LiangHsi-Chin WuHsueh-Chun LinJong-Yi WangTsai-Chung LiYi-Chun YehChih-Hung Chang
Credits/Source: Health and Quality of Life Outcomes 2012, 10:96



Published on: 2012-08-20



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